The biopharmaceutical company that helped Iceland process COVID tests throughout the pandemic is now set to join another important project: the battle to eradicate the fatal disease scrapie from the Icelandic sheep population. RÚV reports that this spring, deCODE genetics will begin analysing genetic material from sheep to determine whether they carry a genotype that protects against the degenerative disease. Scrapie was recently diagnosed at a farm in Northwest Iceland, in a region where it had never been detected before.
Scrapie is often described as the ovine equivalent of mad cow disease. If a sheep tests positive for scrapie, the entire herd is culled, the entire farm’s hay must be destroyed, and the farm and its implements must be sanitised, either chemically or through fire. Even despite these measures, the disease can remain dormant in the environment for decades. The disease takes both a financial and emotional toll on farmers.
Researchers have recently discovered two genotypes in the Icelandic breed of sheep that appear to protect the animals from scrapie: ARR and T137. Breeding programs with those sheep have begun in efforts to eradicate the disease from Iceland.
Until now, Icelandic researchers have had to send genetic samples to Germany for analysis in order to determine whether sheep carry the protective genotypes. With the help of deCODE genetics, it would be possible to test the samples locally. Researchers hope to test the existing stock more broadly as well as, of course, the offspring of the sheep that have already been found to carry the genotypes to see whether they have been passed down.
“If this collaboration with deCODE genetics works out, then hopefully it will be possible to test these samples in Iceland,” stated Eyþór Einarsson of the Icelandic Agricultural Advisory Centre. “And they also have a large capacity, and can handle the project, because the number of samples that will need to be analysed will multiply in the coming years as we get more rams in circulation that carry these genotypes.” Eyþór stated that there could be as many as 40,000 samples that need analysis by next year, and further research into the existing stock would also be necessary.
“This is really exciting and gives us hope and optimism for the future that there is a sort of definite response to this scrapie issue.”